epi-, ep- (11/32)

The medical prefix term ep(i)- means “above”.

Example Word: ep(i)/derm/is

Word Breakdown: Ep(i)- means “above”, derm is a word root that refers to the “skin”, -is is noun ending suffix with no specific meaning.

Definition: A layer of tissue that forms the outermost layer of skin is referred to as the epidermis.

More Examples of Medical Terms Starting in Epi-

Epidemic: epi– (“upon” or “on”) + demos (“people”) + –ic (“pertaining to”).

Definition: A widespread occurrence of an infectious disease in a community at a particular time.


Epididymis: epi– (“upon” or “on”) + didym (“testicle”) + –is (“pertaining to”).

Definition: A tube in the male reproductive system that stores and transports sperm.


Epiglottis: epi– (“upon” or “on”) + glott (“tongue”) + –is (“pertaining to”).

Definition: A flap of cartilage in the throat that covers the opening to the larynx during swallowing.


Epilepsy: epi– (“upon” or “on”) + lepsy (“seizure”).

Definition: A neurological disorder characterized by recurrent seizures.


Epinephrine: epi– (“upon” or “on”) + nephr/o (“kidney”) + –ine (“related to”).

Definition: A hormone produced by the adrenal gland that increases heart rate and blood pressure.


Epistaxis: epi– (“upon” or “on”) + –staxis (“a dropping or falling”).

Definition: Nosebleed.


Epithelium: epi– (“upon” or “on”) + thel (“nipple”) + –ium (“pertaining to”).

Definition: A layer of cells that lines the surfaces and organs of the body.